Table 3.
BLA ramp-evoked activity in sGC and iGCa
| sGC | iGC | |||||
|---|---|---|---|---|---|---|
| Baseline | Ramp | After ramp | Baseline | Ramp | After ramp | |
| PYR | ||||||
| Amplitude (pA) | 11.8 ± 0.2 | 13.9 ± 0.2 | 12.7 ± 0.2 | 12.8 ± 0.30 | 13.3 ± 0.3 | 11.8 ± 0.3 |
| sGC (n = 15) | ||||||
| Instantaneous frequency (Hz) | 27.5 ± 0.8 | 42.0 ± 0.9 | 37.3 ± 0.9 | 15.7 ± 0.6 | 33.8 ± 1.0 | 24.1 ± 0.9 |
| iGC (n = 10) | ||||||
| % change (total charge) | - | 209.8 ± 54.6 | 98.7 ± 20.3 | - | 84.2 ± 16.8 | 47.0 ± 10.1 |
| FS-PV | ||||||
| Amplitude (pA) | 23.7 ± 5.5 | 22.1 ± 1.3 | 25.3 ± 5.5 | 15.3 ± 0.9 | 21.6 ± 1.4 | 19.5 ± 1.2 |
| sGC (n = 2) | ||||||
| Instantaneous frequency (Hz) | 26.7 ± 2.0 | 43.1 ± 2.4 | 33.0 ± 2.0 | 37.5 ± 2.5 | 58.2 ± 2.7 | 46.4 ± 2.7 |
| iGC (n = 2) | ||||||
| % change (total charge) | - | 41.9 ± 24.2 | 24.4 ± 12.3 | - | 77.6 ± 47.6 | 9.1 ± 11.0 |
| RSNP-SOM | ||||||
| Amplitude (pA) | 11.8 ± 0.3 | 13.5 ± 0.4 | 12.1 ± 0.3 | 17.1 ± 0.5 | 17.6 ± 0.6 | 17.2 ± 0.6 |
| sGC (n = 4) | ||||||
| Instantaneous frequency (Hz) | 31.3 ± 1.2 | 46.1 ± 2.1 | 39.1 ± 2.2 | 22.2 ± 1.2 | 39.0 ± 1.5 | 32.4 ± 1.3 |
| iGC (n = 5) | ||||||
| % change (total charge) | - | 133.4 ± 79.2 | 39.7 ± 19.8 | - | 68.0 ± 9.8 | 48.4 ± 29.1 |
-
↵aAverage total synaptic charge onto PYR, FS-PV, and RSNP-SOM neurons located in sGC and iGC before, during, and after asynchronous activation of BLA afferents. Data are mean ± SE.